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About tPEMF Technology

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Targeted pulsed electromagnetic fields (tPEMF)
are simply delivery systems for inducing electromagentic currents. Pulsing an electromagnetic field near a conductor (such as tissue) will induce current flow in the conductor.

tPEMF transmits gentle pulses of therapy into tissues and cells to deliver a therapeutic electronic field to injured tissues This electric field helps activate the body’s natural anti-inflammatory response to injured tissue. The electric fields transmitted into tissues and cells are gentle and safe – Enonovo's tPEMF products emit a pulsed electromagnetic field that has 1,000 times LESS power than your mobile phone.

Simply put, tPEMF uses targeted electromagnetic fields to transmit gentle pulses to the tissue to help reduce pain and swelling and speed up the body's natural recovery process.

Endonovo SofPulse® Mechanism of Action Video 2019

Endonovo SofPulse® Mechanism of Action Video 2019

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Mechanism of Action

Mechanism of Action

Right down to the cellular level, the body works on an electro-chemical basis. In fact, all activity in the body is caused or facilitated by electrically driven binding processes. tPEMF has been shown in multiple publications to affect the electro-chemical process that triggers the release of nitric oxide — the first step in the body’s natural
anti-inflammatory response.

  • tPEMF is placed on the desired treatment area (treatment depth is
    5” and works through dressings, casts and clothing)

  • The body responds within milliseconds by releasing nitric oxide, the
    body’s own natural anti-inflammatory chemical.

  • The blood vessels respond by smoothing out and allowing greater blood flow. 
    This reduces pain and edema.

  • Downstream growth factors are released (hours to days)

  • Angiogenesis occurs (days to weeks)

explanation of targeted tPEMF mechanisim

Regulatory Approvals and Industry Guidelines

Regulatory Approvals

  • FDA Cleared for treating post-operative pain and edema in soft tissue

  • CE mark for the treatment of pain, wounds and edema (Class 2a)

  • CMS national coverage determination for PEMF for chronic wounds

NPUAP and EPUAP (2016 Guidelines)

  • Consider the use of pulsed electromagnetic field (PEMF) treatment for recalcitrant Category/Stage II pressure injuries as well as any Category/ /Stage III and IV pressure injury

  • Rated as comparable to NPWT (in relation to clinical evidence)

  • The body does not respond to the low energy signal unless there is inflamed tissue so there is no danger of overdose

  • American Society of Aesthetic Plastic Surgeons endorses use of tPEMF (2001) 

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